Related Experiment Video
Updated: Jul 3, 2026

Measuring DNA Damage and Repair in Mouse Splenocytes After Chronic In Vivo Exposure to Very Low Doses of Beta- and Gamma-Radiation
Published on: July 3, 2015
[Diuron degradation process and change of toxicity by gamma-irradiation]
Ji-Biao Zhang1, Zheng Zheng, Lin Ye
1State Key Laboratory of Pollution Control and Resource Reuse, School of the Environment, Nanjing University, Nanjing 210093, China. zhangjb33@126.com
Abstract:
The radiation-induced degradation process of diuron and change of toxicity by gamma-irradiation were investigated. The contribution to diuron degradation by the radicals is in the order of: *OH > e(aq)(-) > *H. The quantum efficiency ratios of *OH, e(aq)(-) and *H for the degradation of diuron are calculated as 3 : 1 : 2. e(aq)(-) and *H could reduce diuron and its degradation product by loss of the chlorine atoms and the addition reaction. Both the shift and alkaline substitute mutations firstly increase and then decrease with the increase of irradiation time. But, the sample only shows mutagenic potential in Ames assay (TA100 strain) when 22.2 min is selected as the irradiation time. The acute toxicity firstly decreases and then increases with the increase of irradiation time and the more toxic substances are produced.
More Related Videos
Related Concept Videos
Microbial Bioremediation of Uranium
Biological Effects of Radiation
Mutations
Chromosomal Alterations Are Large-Scale Mutations
While point mutations are changes in a single nucleotide in...
Microbial Bioremediation of Pesticides
Other Unique Bacteria
Enhanced Elimination of Poison
Antidotes serve a crucial role in counteracting the effects of poison by inhibiting enzymes responsible for producing harmful drug metabolites. In some cases, these toxic metabolites can be neutralized by endogenous cosubstrates, which are maintained at specific concentrations to prevent interaction with cellular macromolecules and subsequent cell death.
Renal excretion is the...

