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Related Concept Videos

Ultrasound II: Endoscopic Ultrasound and FibroScan01:25

Ultrasound II: Endoscopic Ultrasound and FibroScan

Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
Endoscopic Ultrasound (EUS):
Ultrasonography01:17

Ultrasonography

Ultrasonography is an imaging technique that uses high-frequency sound waves to visualize the body's internal structures. It is a non-invasive and safe procedure that does not involve the use of ionizing radiation, making it widely used in various medical fields. Ultrasonography is used to study heart function, blood flow in the neck or extremities, certain conditions such as gallbladder disease, and fetal growth and development.
During an ultrasonography procedure, a handheld device called a...
Imaging Studies for Cardiovascular System II:Types of Echocardiography01:20

Imaging Studies for Cardiovascular System II:Types of Echocardiography

Echocardiography plays a role in assessing cardiac health and detecting heart conditions, with various types providing critical insights for diagnosis and treatment.
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for diagnosing...

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Related Experiment Video

Updated: Jul 3, 2026

Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis
05:56

Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis

Published on: August 29, 2025

Transient elastography: Applications and limitations.

Kentaro Yoshioka1, Naoto Kawabe, Senju Hashimoto

  • 1Division of Liver, Biliary Tract and Pancreas Diseases, Department of Internal Medicine, Fujita Health University, Aichi, Japan.

Hepatology Research : the Official Journal of the Japan Society of Hepatology
|July 16, 2008
PubMed
Summary

Transient elastography (FibroScan) accurately assesses liver fibrosis but requires cautious interpretation due to variations. Combining it with other noninvasive methods like FibroTest improves staging accuracy.

Related Experiment Videos

Last Updated: Jul 3, 2026

Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis
05:56

Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis

Published on: August 29, 2025

Area of Science:

  • Hepatology
  • Medical Imaging
  • Diagnostic Technologies

Background:

  • Transient elastography (TE) using FibroScan is a highly accurate, operator-friendly method for assessing liver fibrosis.
  • Studies show good correlation between liver stiffness measurements (LSM) via TE and fibrosis stages across various liver diseases.
  • However, LSM exhibits variability within stages and overlap between adjacent stages, necessitating careful interpretation.

Purpose of the Study:

  • To evaluate the accuracy and limitations of transient elastography for liver fibrosis staging.
  • To identify factors influencing liver stiffness measurements.
  • To recommend strategies for improving the accuracy of noninvasive liver fibrosis assessment.

Main Methods:

  • Review of studies utilizing transient elastography (FibroScan) for liver fibrosis assessment.
  • Analysis of correlation between liver stiffness measurements and established fibrosis stages.
  • Identification of confounding factors affecting LSM reproducibility.

Main Results:

  • TE demonstrates high accuracy in liver fibrosis staging with consistent cutoff values across diseases.
  • Significant variations in stiffness values exist within the same fibrosis stage, with overlap between adjacent stages.
  • Factors such as inflammatory activity, cirrhosis nodule size, age, obesity, steatosis, and intercostal space impact LSM reproducibility.

Conclusions:

  • While TE is a valuable tool, liver fibrosis staging requires cautious interpretation due to inherent variability and influencing factors.
  • Combining TE with other noninvasive methods, such as FibroTest, is recommended to enhance the accuracy of liver fibrosis staging.