Headache secondary to psychiatric disorders
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Updated: Jul 3, 2026

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Published on: June 2, 2014
Todd A Smitherman1, Steven M Baskin
1Head Pain Center, Department of Psychiatry and Human Behavior, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USA. tsmitherman@residents.umsmed.edu
Abstract:
Recent literature shows an interest in the relationship between psychiatric disorders and headache. This relationship is complex and multifaceted, with existing studies confirming high rates of comorbidity between psychiatric disorders (especially depression and anxiety) and migraine and tension-type headache, implicating comorbid psychiatric disorders as risk factors for headache progression and chronification, and underscoring the need for assessment and treatment of relevant disorders. A smaller amount of literature has focused on headache that presents exclusively during and secondary to a psychiatric disturbance; this phenomenon has been termed "headache attributed to psychiatric disorder." We review recent developments in the relationship between psychiatric conditions and headache, with a particular focus on headaches attributed to psychiatric disorders, and discuss needed areas for future research.
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