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Identification of nucleoli in the early branching protist Giardia duodenalis

Luis Felipe Jiménez-García1, Guadalupe Zavala, Bibiana Chávez-Munguía

  • 1Departamento de Biología Celular, Facultad de Ciencias-Universidad Nacional Autónoma de México, Mexico City, Mexico.

International Journal for Parasitology
|July 16, 2008
PubMed

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Giardiasis is a globally prevalent intestinal infection caused by the protozoan parasite Giardia duodenalis (also known as G. lamblia or G. intestinalis). This flagellated protozoan is the most frequently identified intestinal parasite in the United States and worldwide. Transmission primarily occurs via the fecal-oral route, with infection arising from ingestion of water or food contaminated with cysts. Individuals in low-resource settings, international travelers, outdoor enthusiasts, daycare...
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The nucleolus is the most prominent substructure of the nucleus. When it was first discovered, it was considered to be an isolated organelle that forms fibrils and granules. In 1931, the relationship between the nucleolus and chromosomes was first described by Heitz. He observed that the appearance and size of nucleolus varies depending on the stage of the cell cycle. He also noticed constricted regions on different chromosomes clustered together at definite cell cycle stages. These regions,...