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Experience with intrapleural natural beta interferon in the treatment of malignant pleural effusions
S Cascinu1, P P Isidori, A Fedeli
1Servizio di Oncologia, Ospedali Riuniti, Pesaro, Italy.
Tumori
|June 30, 1991
Abstract:
Malignant pleural effusion is a common complication of cancer. Intrapleural beta interferon has been recently tested, and responses were obtained in about 1/3 of the patients without considerable side effects. We treated 22 patients with recurrent symptomatic malignant pleural effusions with intrapleural beta interferon at increasing doses (5-15 million units) for a maximum of three courses and obtained only two responses. In our opinion, this schedule cannot be recommended for routine use.