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Updated: Jul 3, 2026
Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance
Published on: June 6, 2025
Prostate carcinoma spatial distribution patterns in Chinese men investigated with systematic transperineal ultrasound
Weigang Yan1, Hanzhong Li, Yi Zhou
1Department of Urology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Objectives:
To evaluate prostate cancer spatial distribution patterns with transperineal ultrasound navigated 11-region prostate biopsy template in a Chinese screening population.
Methods:
From May 2004 to December 2007, 215 patients with a median prostate-specific antigen (PSA) level of 21.0 ng/ml were diagnosed with prostate cancer through transperineal ultrasound guided 11-region template prostate biopsy at Peking Union Medical College Hospital. The characteristics of our sample cancer spatial distribution were assessed in relation with different PSA levels.
Results:
The mean positives for the cancer of regions 1-10 and region 11 (the apical region) were 61.2% vs. 66.4% in patients whose PSA > 20 ng/ml (P = 0.29), and 35.7% vs. 47.6% in patients with PSA
Conclusions:
The current study suggests that prostate carcinoma foci are more frequently localized in the apical region in patients with normal to moderately increased PSA. Special attention should be paid to the apical region during the selection process of biopsy regions for this group of patients.
