[Incidence of cholelithiasis after its experimental induction by various methods]

The incidence rate of cholelithiasis was studied in varying methods of lithogenic stimulation: a diet enriched with cholesterol and chenodesoxycholic acid, induction of acute aseptic inflammation of the gallbladder by thermal damage, and the use of ++anti-gallbladder sera. The results of the study have shown almost similar (44-52%) reproducibility of cholelithiasis in guinea pigs, the development of pigment concrements was recorded in the absolute majority of cases. Correlation of the cholelithiasis incidence rate with inflammatory disorders in the gallbladder has evidenced the importance of the immunoallergic component in the determination of acute cholelithiasis and cholelithiasis, where cholelithiasis shows its secondary character.