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Published on: December 5, 2025
Update on perioral cosmetic enhancement
1Department of Otolaryngology and Communication Sciences, Upstate Medical University, Syracuse, New York 13210, USA. amarsuryad@yahoo.com
Summary
Rejuvenating the aged perioral region is now safer and more effective with advanced techniques. Minimally invasive options like soft tissue fillers, fat grafting, and botulinum toxin offer natural-looking results for wrinkles and volume loss.
Area of Science:
- Aesthetic Medicine
- Dermatology
- Plastic Surgery
Background:
- The perioral region presents unique aging challenges.
- Traditional rejuvenation methods included surgical excision, chemical peels, and laser resurfacing.
- Advances in understanding and techniques have improved safety and efficacy.
Purpose of the Study:
- To review recent literature on perioral region rejuvenation.
- To discuss minimally invasive techniques for age-related perioral changes.
- To highlight combined modality approaches for optimal aesthetic outcomes.
Main Methods:
- Review of current literature on perioral rejuvenation techniques.
- Analysis of minimally invasive procedures including chemodenervation, soft tissue fillers, and fat grafting.
- Evaluation of techniques for rhytids, folds, and lip thinning.
Main Results:
- Chemodenervation, soft tissue fillers, fat grafting, and dermabrasion are key rejuvenation modalities.
- These techniques effectively address wrinkles, folds, and volume loss in the perioral area.
- Combination therapies often yield the most natural aesthetic results.
Conclusions:
- Modern techniques allow effective and low-risk rejuvenation of the aged perioral area.
- Soft tissue fillers and autologous fat are optimal for addressing volume loss.
- Botulinum toxin and facial resurfacing remain crucial for wrinkles and deeper rhytids.