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Related Experiment Video

Updated: Jul 3, 2026

Protocol to Create Chronic Wounds in Diabetic Mice

Protocol to Create Chronic Wounds in Diabetic Mice

Published on: September 25, 2019

Wound healing from a cellular stress response perspective.

Bindi M Doshi¹, George A Perdrizet, Lawrence E Hightower

¹Department of Molecular and Cell Biology, The University of Connecticut, Storrs, CT 06269, USA.

Cell Stress & Chaperones

|July 16, 2008

Summary

Cellular stress and wound healing research share common interests in inflammation control. This review explores overlapping areas and collaboration potential between these fields, particularly for chronic wounds.

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Area of Science:

Cellular biology
Immunology
Regenerative medicine

Background:

Inflammation is a key factor in adult wound healing.
Cellular stress response mechanisms are relevant to wound repair.
Chronic non-healing wounds, often linked to diabetes and vascular diseases, present a significant clinical challenge.

Framework:

This review focuses on the intersection of cellular stress response and wound healing research.
It highlights inflammation as a central unifying theme.
The authors' perspective is shaped by an interest in chronic non-healing wounds.

Implementation:

The review synthesizes findings from recent investigations in both fields.
It identifies shared interests and potential areas for interdisciplinary collaboration.
Specific examples of overlapping research topics are discussed.

Implications:

Understanding the interplay between cellular stress and inflammation can advance wound healing therapies.
Interdisciplinary collaboration between stress response and wound healing researchers can accelerate discoveries.
This work may lead to improved treatments for chronic wounds, benefiting patients with diabetes and vascular diseases.