Related Experiment Video
Updated: Jul 3, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
Pruritic bluish-black subcutaneous papules on the chest
Vivian T Laquer1, Jashin J Wu, Joshua A Tournas
1College of Physicians & Surgeons, Columbia University, New York, NY, USA.
Abstract:
Steatocystoma multiplex (SM) is characterized by multiple dermal cysts involving the pilosebaceous glands. Although most presenting cases are sporadic, there is a rare familial syndrome involving a mutation in keratin 17 (K17) that is inherited in an autosomal dominant fashion. SM often presents concomitantly with eruptive vellus hair cysts (EHVS) and pachyonychia congenital type 2 (PC-2). We report a sporadic case of SM in a 21-year-old man.
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