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Updated: Jul 3, 2026

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Isolation of Papillary and Reticular Fibroblasts from Human Skin by Fluorescence-activated Cell Sorting
Published on: May 7, 2019
Friction induced skin tags.
Francisco Allegue1, Carmen Fachal, Lidia Pérez-Pérez
1Department of Dermatology, Complejo Hospitalario Universitario de Vigo Vigo, Spain. fallegue@mundo-r.com
Dermatology Online Journal
|July 17, 2008
Summary
Skin tags are common benign neoplasms. A case study suggests friction may play a role in their development, particularly when they appear in a linear pattern.
Area of Science:
- Dermatology
- Neoplastic disease research
Background:
- Skin tags, also known as acrochorda, are frequent benign neoplasms.
- They predominantly occur in intertriginous areas of the skin.
- Current treatments include cryotherapy, electrodessication, and snip-excision, primarily addressing cosmetic concerns.
Observation:
- A patient presented with multiple skin tags.
- These skin tags were notably arranged in a distinct linear fashion.
- This presentation is unusual and prompts further investigation into the cause.
Findings:
- The linear arrangement of skin tags suggests a potential etiopathogenic factor.
- Friction is proposed as a possible contributing factor to the development of these neoplasms.
- This observation contrasts with the generally scarce data on skin tag etiopathogenesis.
Implications:
- Understanding the role of friction in skin tag development could inform preventative strategies.
- Further research into friction-induced neoplasm formation is warranted.
- This case highlights the need for more data on the origins of common skin conditions.
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