Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Pseudolymphoma evolving into diffuse large B-cell lymphoma.

Niroshana Anandasabapathy¹, Melissa Pulitzer, Wendy Epstein

¹Department of Dermatology, New York University, USA.

Dermatology Online Journal

|July 17, 2008

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Langerhans cell control of early-life dermal lymphatic development shapes adult immunity.

Science immunology·2026

Same author

Interobserver Variability Across Whole-Slide Imaging Systems.

Archives of pathology & laboratory medicine·2026

Same author

Mechanistic insights into emerging therapeutic platforms: The 72<sup>nd</sup> annual Montagna Symposium on the Biology of Skin.

The Journal of investigative dermatology·2026

Same author

Correction: Hsu et al. Vaccinia Virus: Mechanisms Supporting Immune Evasion and Successful Long-Term Protective Immunity. <i>Viruses</i> 2024, <i>16</i>, 870.

Viruses·2026

Same author

Non-JAK-family gene fusions in cutaneous T-cell lymphoma highlights genetic diversity and potential therapeutic targets.

Haematologica·2026

Same author

Peripheral immune-inducer dendritic cells drive early-life allergic inflammation.

Nature·2026

Same journal

Pellagra associated with iron deficiency.

Dermatology online journal·2026

Same journal

Demodicosis: A frequently underrecognized cause of recalcitrant ear pruritus.

Dermatology online journal·2026

Same journal

Association of alopecia areata with COVID-19 vaccination: A vaccine adverse events reporting system analysis.

Dermatology online journal·2026

Same journal

Gender based price differences in 5% minoxidil foam: The impact of generic alternatives and bulk packaging.

Dermatology online journal·2026

Same journal

Retrospective analysis of filler complications reported in the manufacturer and user facility device experience database from 2015 to 2025.

Dermatology online journal·2026

Same journal

Characterizing barriers to care in patients with hidradenitis suppurativa.

Dermatology online journal·2026

See all related articles

A rare case of pseudolymphoma transforming into diffuse large B-cell lymphoma (DLBCL) highlights diagnostic challenges. This transformation, confirmed by gene rearrangement, indicates an intermediate prognosis for this specific DLBCL subtype.

Area of Science:

Dermatology
Hematology
Oncology

Background:

Pseudolymphoma presents as benign lymphoid hyperplasia.
Distinguishing pseudolymphoma from lymphoma is crucial for appropriate treatment.
T-cell-rich, large B-cell lymphoma (TRBCL) is an aggressive non-Hodgkin lymphoma.

Observation:

A 46-year-old man developed asymptomatic papules on his arm.
Initial diagnosis was pseudolymphoma treated with glucocorticoids.
Recurrent lesions evolved into T-cell-rich, large B-cell lymphoma with gene rearrangement.

Findings:

The patient exhibited a rare transformation from pseudolymphoma to diffuse large B-cell lymphoma (DLBCL).
Monoclonal immunoglobulin light chain gene rearrangement confirmed the malignant nature of the transformed lesions.

Related Experiment Videos

Systemic evaluation revealed no extracutaneous involvement.

Implications:

This case underscores the importance of vigilant follow-up for suspected pseudolymphoma.
The patient's subtype of DLBCL carries an intermediate prognosis.
Treatment options may include local radiotherapy, chemotherapy, and rituximab.