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Updated: Jul 3, 2026

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
Published on: May 1, 2015
Lymphangioma circumscriptum
Marissa Heller1, Stephanie Mengden
1Department of Dermatology, New York University, USA.
Abstract:
A 54-year-old man presented for evaluation of multiple 1- to-4-mm, clear, pink, red, and black vesicles overlying hyperpigmented and erythematous indurated plaques on his right thigh and extending to his right inguinal fold. Clinical presentation and histopathologic features were consistent with lymphangioma circumscription. Lymphangioma circumscriptum is the most common cutaneous form of lymphangioma. Typical skin findings are multiple clear vesicles that may appear pink, red, or black. The first-line treatment option is surgical excision, although other modalities, such as laser therapy and sclerotherapy, have also been used successfully.
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