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Updated: Jul 3, 2026

Advanced Animal Model of Colorectal Metastasis in Liver: Imaging Techniques and Properties of Metastatic Clones
Published on: November 30, 2016
Clinical case report and literature review: metachronous colorectal splenic metastases
J M Gasent Blesa1, E de la Morena, J B Laforga Canales
1Medical Oncology Department, Hospital Marina Alta, Dènia, Alacant, Spain. joanmagasent @telefonica.net
Abstract:
A 52-year-old woman with a rising carcinoembryonic antigen CEA, no clinical or radiological findings, a negative colonoscopy, and a positron emission tomography (PET) scan that revealed an isolated hypermetabolic lesion in the spleen. The patient underwent splenectomy by laparoscopic surgery. The pathological study confirmed the presence of an isolated metastasis to the spleen. This case reveals the rare occurrence of isolated splenic metastases in the context of colorectal cancer and illustrates the role of PET when a patient shows a rising CEA with negative clinicoradiological studies.