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Testing the Efficacy of Pharmacological Agents in a Pericardial Target Delivery Model in the Swine
10:05

Testing the Efficacy of Pharmacological Agents in a Pericardial Target Delivery Model in the Swine

Published on: July 7, 2016

[Pharmacological protection of pregnant women with heart defects during abdominal delivery]

S I Generalov, T P Kaban'ko, V S Kostenko

    Akusherstvo I Ginekologiia
    |April 1, 1991
    PubMed

    The drug salvage developed by the authors was studied for its impact on maternal, fetal, neonatal homeostasis, the incidence of unfavourable outcomes in the mother and her fetus in 40 pregnant with cardiac malformations whose pregnancy was delivered via cesarean section as a planned operation. The baseline hypodynamic circulation was detected in pregnant with heart disease. This was found to be steady-state during the operation and the drug salvage was adequate in the females. This showed a 2.7- or 2.0-fold reduction in maternal cardiovascular events and unfavourable neonatal sequelae, respectively.

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