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Photonic crystal resonator integrated in a microfluidic system.

P S Nunes1, N A Mortensen, J P Kutter

  • 1Department of Micro- and Nanotechnology, Technical University of Denmark, Lyngby, Denmark. pedro.nunes@nanotech.dtu.dk

Optics Letters
|July 17, 2008
PubMed
Summary

This study introduces a new optofluidic system for label-free refractive index detection using a photonic crystal resonator. The system achieves high sensitivity for analyzing ethanol solutions, demonstrating its potential in chemical sensing.

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Area of Science:

  • Optofluidics
  • Photonic Crystals
  • Biosensing

Background:

  • Label-free detection methods are crucial for real-time analysis in microfluidic systems.
  • Photonic crystals offer unique light-matter interaction properties for sensing applications.
  • Electrochromatography platforms require sensitive detection for analyzing separated components.

Purpose of the Study:

  • To develop and characterize a novel optofluidic system for label-free refractive index detection.
  • To integrate a 1D photonic crystal resonator with microfluidic channels for on-column analysis.
  • To evaluate the system's sensitivity and detection limits using ethanol-water solutions.

Main Methods:

  • Fabrication of a silicon oxynitride-based 1D photonic crystal with integrated waveguides and fluidic channels.

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  • Utilizing an array of pillars within the microfluidic channel as a resonator for electrochromatography.
  • Operating the system at a wavelength of 1.55 micrometers and measuring transmission spectra of ethanol solutions.
  • Analyzing linear shifts in resonant wavelengths to determine refractive index sensitivity.
  • Main Results:

    • The optofluidic system demonstrated label-free refractive index detection.
    • A maximum sensitivity of 480 nm/RIU (refractive index unit) was achieved.
    • A minimum detectable refractive index difference of 0.007 RIU was measured.
    • The system successfully analyzed aqueous solutions of ethanol with varying refractive indices.

    Conclusions:

    • The developed optofluidic system provides a sensitive platform for label-free refractive index sensing.
    • The integration of photonic crystals and microfluidics enables on-column detection in electrochromatography.
    • This technology holds promise for applications in chemical analysis and diagnostics.