Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Diversity of Protists I

Diversity of Protists I

Excavata is a diverse group of protists that includes both chemoorganotrophic and phototrophic species, with some thriving in anaerobic environments. Among the key groups within Excavata are diplomonads and parabasalids, which are flagellated protists that lack mitochondria and chloroplasts. These microorganisms typically inhabit anoxic environments, such as the intestines of animals, where they exist either symbiotically or as parasites, relying on fermentation for energy production. Some...

Fungal Phylum Microsporidia

Fungal Phylum Microsporidia

Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...

Genomic DNA in Eukaryotes

Genomic DNA in Eukaryotes

Eukaryotes have large genomes compared to prokaryotes. To fit their genomes into a cell, eukaryotic DNA is packaged extraordinarily tightly inside the nucleus. To achieve this, DNA is tightly wound around proteins called histones, which are packaged into nucleosomes that are joined by linker DNA and coil into chromatin fibers. Additional fibrous proteins further compact the chromatin, which is recognizable as chromosomes during certain phases of cell division.

Genomic DNA in Prokaryotes

Genomic DNA in Prokaryotes

The genome of most prokaryotic organisms consists of double-stranded DNA organized into one circular chromosome in a region of cytoplasm called the nucleoid. The chromosome is tightly wound, or supercoiled, for efficient storage. Prokaryotes also contain other circular pieces of DNA called plasmids. These plasmids are smaller than the chromosome and often carry genes that confer adaptive functions, such as antibiotic resistance.
Genomic Diversity in Bacteria
Although bacterial genomes are much...

Evolution of Microbial Genome

Evolution of Microbial Genome

Microbial genome evolution is a highly dynamic process shaped by continual gene gain and loss across species and strains. This genomic flexibility allows microorganisms to adapt rapidly to environmental pressures and interactions with other organisms. Central to understanding this diversity is the distinction between the core and pan genomes.The core genome comprises the genes shared by all sampled strains of a species, representing essential functions needed for fundamental cellular processes.

Comparing Mitochondrial, Chloroplast, and Prokaryotic Genomes

Comparing Mitochondrial, Chloroplast, and Prokaryotic Genomes

The present-day mitochondrial and chloroplast genomes have retained some of the characteristics of their ancestral prokaryotes and also have acquired new attributes during their evolution within eukaryotic cells. Like prokaryotic genomes, mitochondrial and chloroplast genomes neither bind with histone-like proteins nor show complex packaging into chromosome-like structures, as observed in eukaryotes. Unlike mitotic cell divisions observed in eukaryotic cells, mitochondria and chloroplasts...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Large-scale investigation of the parameters in response to Eimeria maxima challenge in broilers.

Journal of animal science·2015

Same author

Fecundity of Cryptosporidium parvum is correlated with intracellular levels of the viral symbiont CPV.

International journal for parasitology·2007

Same author

Gene expression and antimicrobial activity of bovine macrophages in response to Mycobacterium avium subsp. paratuberculosis.

Veterinary pathology·2004

Same author

Pharmacological inhibition of Mannheimia haemolytica lipopolysaccharide and leukotoxin-induced cytokine expression in bovine alveolar macrophages.

Microbial pathogenesis·2004

Same author

Microarray-based expression analysis of human epithelial cell response to Cryptosporidium parvum infection.

The Journal of eukaryotic microbiology·2002

Same author

Sequence analysis of the nucleocapsid and phosphoprotein genes of avian pneumoviruses circulating in the US.

Virus research·2001

Same journal

Screen for Footprints of Selection during Domestication/Captive Breeding of Atlantic Salmon.

Comparative and functional genomics·2013

Same journal

Gemi: PCR primers prediction from multiple alignments.

Comparative and functional genomics·2013

Same journal

TnpPred: A Web Service for the Robust Prediction of Prokaryotic Transposases.

Comparative and functional genomics·2012

Same journal

The α(1)AT and TIMP-1 Gene Polymorphism in the Development of Asthma.

Comparative and functional genomics·2012

Same journal

Comparative Analysis of MicroRNAs between Sporophyte and Gametophyte of Porphyra yezoensis.

Comparative and functional genomics·2012

Same journal

Correlation of aquaporins and transmembrane solute transporters revealed by genome-wide analysis in developing maize leaf.

Comparative and functional genomics·2012

See all related articles

Search research articles

Related Experiment Video

Updated: Jul 3, 2026

Studying Cryptosporidium Infection in 3D Tissue-derived Human Organoid Culture Systems by Microinjection

Studying Cryptosporidium Infection in 3D Tissue-derived Human Organoid Culture Systems by Microinjection

Published on: September 14, 2019

Cryptosporidium parvum genome project.

M S Abrahamsen¹

¹Veterinary PathoBiology, University of Minnesota, 1988 Fitch Avenue, St. Pau,l MN 55108, USA. abe@umn.edu

Comparative and Functional Genomics

|July 17, 2008

Summary

This summary is machine-generated.

Sequencing the Cryptosporidium parvum genome provides crucial insights into parasite biology. This knowledge is essential for developing targeted treatments and prevention strategies against this important pathogen.

More Related Videos

Generating Genetically Modified Plasmodium berghei Sporozoites

Generating Genetically Modified Plasmodium berghei Sporozoites

Published on: May 5, 2023

Related Experiment Videos

Last Updated: Jul 3, 2026

Studying Cryptosporidium Infection in 3D Tissue-derived Human Organoid Culture Systems by Microinjection

Studying Cryptosporidium Infection in 3D Tissue-derived Human Organoid Culture Systems by Microinjection

Published on: September 14, 2019

Generating Genetically Modified Plasmodium berghei Sporozoites

Generating Genetically Modified Plasmodium berghei Sporozoites

Published on: May 5, 2023

Area of Science:

Parasitology
Genomics
Infectious Diseases

Background:

Limited understanding of Cryptosporidium parvum biology hinders effective disease control.
Genomic information is key to understanding parasite development, pathogenesis, and immune evasion.

Purpose of the Study:

To obtain the complete genome sequence of the IOWA isolate of Cryptosporidium parvum.
To leverage genomic data for advancing research in disease prevention and treatment.

Main Methods:

Random shotgun sequencing approach for large-scale genomic sequencing.
Utilizing advanced high-throughput DNA sequencing and bioinformatics tools for gene discovery.

Main Results:

Genomic sequencing is an efficient and cost-effective method for gene discovery in C. parvum.
The complete genome sequence will facilitate identification of key metabolic and immunological features.

Conclusions:

Complete C. parvum genome sequencing is vital for developing novel prevention and treatment strategies.
Genomic data will enable effective strain typing and epidemiologic surveillance for improved public health outcomes.