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Related Concept Videos

Protein Networks02:26

Protein Networks

An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
Protein Networks02:26

Protein Networks

An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
Protein-protein Interfaces02:04

Protein-protein Interfaces

Many proteins form complexes to carry out their functions, making protein-protein interactions (PPIs) essential for an organism's survival. Most PPIs are stabilized by numerous weak noncovalent chemical forces. The physical shape of the interfaces determines the way two proteins interact. Many globular proteins have closely-matching shapes on their surfaces, which form a large number of weak bonds. Additionally, many PPIs occur between two helices or between a surface cleft and a polypeptide...
C4 Pathway and CAM01:27

C4 Pathway and CAM

Most plants use the C3 pathway for carbon fixation. However, some plants, such as sugar cane, corn, and cacti that grow in hot conditions, use alternative pathways to fix carbon and conserve energy loss due to photorespiration. Photorespiration is the process that occurs when the oxygen concentration is high. Under such conditions, the rubisco enzyme in the Calvin cycle binds O2 instead of CO2, which halts photosynthesis and consumes energy.
C4 Pathway
The C4 pathway is used by plants such as...
Amino Acid Biosynthetic Pathways01:29

Amino Acid Biosynthetic Pathways

Amino acid biosynthesis is essential for cell growth, protein synthesis, and metabolic regulation. Cells generate essential and non-essential amino acids from metabolic intermediates to sustain vital biological functions. These intermediates originate from key metabolic pathways: glycolysis, the tricarboxylic acid (TCA) cycle, and the pentose phosphate pathway. Important precursors include α-ketoglutarate, pyruvate, oxaloacetate, phosphoenolpyruvate, and erythrose-4-phosphate, which provide...

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Related Experiment Video

Updated: Jul 3, 2026

A Web Tool for Generating High Quality Machine-readable Biological Pathways
08:01

A Web Tool for Generating High Quality Machine-readable Biological Pathways

Published on: February 8, 2017

Interoperability of CABRI Services and Biochemical Pathways Databases.

Paolo Romano1, Ottavia Aresu, Maria Assunta Manniello

  • 1National Cancer Research Institute, Genova, Italy. paolo.romano@istge.it

Comparative and Functional Genomics
|July 17, 2008
PubMed
Summary
This summary is machine-generated.

The Common Access to Biological Resources and Information (CABRI) service offers a centralized hub for biological materials from European culture collections. Enhancements include improved catalogue information and links to external scientific databases.

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Area of Science:

  • Microbiology
  • Bioinformatics
  • Resource Management

Background:

  • The Common Access to Biological Resources and Information (CABRI) service functions as a centralized platform for biological resources from European culture collections.
  • It adheres to Quality Guidelines for resource and information management, serving the scientific community.
  • Existing features include searchable catalogues via SRS, synonym search, and a shopping cart.

Purpose of the Study:

  • To enhance and extend the information within the CABRI catalogues.
  • To improve the integration of biological resource data with external scientific databases.
  • To refine data annotation processes for better external linking.

Main Methods:

  • Expanding catalogue content within the European Biological Resource Centres Network (EBRCN) project.
  • Integrating links to bibliographic databanks and sequence databases.
  • Revising internal controlled vocabularies for data annotators.
  • Establishing new links to biochemical pathways databases.

Main Results:

  • Ongoing improvements to the CABRI service are enhancing the accessibility and utility of biological resources.
  • New data links are being established to bibliographic, sequence, and biochemical pathway databases.
  • Controlled vocabularies are being revised to facilitate better external data integration.

Conclusions:

  • The ongoing development of CABRI, particularly through the EBRCN project, is significantly improving access to biological resources and information.
  • Enhanced data linking and improved annotation are crucial for advancing biological research.
  • CABRI continues to evolve as a vital resource for the scientific community.