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Related Concept Videos

Protein Organization01:24

Protein Organization

Proteins are polymers of amino acid residues. They are versatile and responsible for different cellular functions, including DNA replication, molecular transport, catalysis, and structural support. Proteins have a hierarchical structure comprising at least three levels of organization: primary, secondary, and tertiary structure. Some large proteins have a quaternary structure where individual protein subunits are linked together.
The primary structure of a protein is its amino acid sequence.
Protein Organization01:24

Protein Organization

Proteins are polymers of amino acid residues. They are versatile and responsible for different cellular functions, including DNA replication, molecular transport, catalysis, and structural support. Proteins have a hierarchical structure comprising at least three levels of organization: primary, secondary, and tertiary structure. Some large proteins have a quaternary structure where individual protein subunits are linked together.
The primary structure of a protein is its amino acid sequence.
Protein Organization01:13

Protein Organization

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Molecular Models

Physical models representing molecular architectures of chemical compounds play essential roles in understanding chemistry. The use of molecular models makes it easier to visualize the structures and shapes of atoms and molecules.
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Predicting Molecular Geometry

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The DNA Helix

Deoxyribonucleic acid, or DNA, is the genetic material responsible for passing traits from generation to generation in all organisms and most viruses. DNA is composed of two strands of nucleotides that wind around each other to form a spring-like structure called a double helix. However, the double helix is not perfectly symmetrical. Instead, there are regularly occurring grooves in the structure. The major groove occurs where the sugar-phosphate backbones are relatively far apart. This space...

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Application of I TASSER, trRosetta, UCSF Chimera, HADDOCK server, and HEX loria for De Novo and In Silico Design of Proteins
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Workshop--Predicting the structure of biological molecules.

Damian Counsell1

  • 1Rosalind Franklin Centre for Genomics Research, Wellcome Trust Genome Campus, Cambridge CB10 1SB, UK. d.counsell@rfcgr.mrc.ac.uk

Comparative and Functional Genomics
|July 17, 2008
PubMed
Summary

UK researchers met to discuss computational biomolecular structure prediction and protein evolution. The workshop highlighted the robust and active state of structural bioinformatics in the United Kingdom.

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Area of Science:

  • Structural Bioinformatics
  • Computational Biology
  • Protein Science

Background:

  • The Medical Research Council's National Institute of Medical Research hosted a workshop.
  • The event focused on computational approaches in biology.

Purpose of the Study:

  • To bring together UK researchers in structural bioinformatics.
  • To discuss advancements in biomolecular structure prediction and analysis.
  • To explore computational work in protein evolution.

Main Methods:

  • Workshop organization and presentations.
  • Discussions on computational work.
  • Sharing of research findings.

Main Results:

  • Attendees gained an overview of protein bioinformatics in the UK.
  • The meeting fostered discussion on biomolecular structure prediction.
  • Protein evolution research was a key topic.

Conclusions:

  • Structural bioinformatics in the UK is in a healthy state.
  • The workshop facilitated a productive exchange of ideas.
  • Collaboration and discussion are vital for advancing the field.