Related Experiment Video
Updated: Jul 3, 2026
07:59
A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
A new secolactarane-type sesquiterpene from Strobilurus tephanocystis
Fuminori Hiramatsu1, Tetsuya Murayama, Takuya Koseki
1Faculty of Agriculture, Department of Bioresource Engineering, Yamagata University, Tsuruoka, Yamagata 997-8555, Japan.
Natural Product Research
|July 17, 2008
Summary
A novel sesquiterpenoid, strobiluric acid, was identified from the fungus Strobilurus stephanocystis. This discovery adds to the known compounds isolated from this fungal species.
Area of Science:
- Natural Product Chemistry
- Mycology
- Organic Chemistry
Background:
- Fungal secondary metabolites are a rich source of novel chemical structures.
- The fungus Strobilurus stephanocystis is known to produce various bioactive compounds.
Purpose of the Study:
- To isolate and characterize new chemical entities from the liquid culture of Strobilurus stephanocystis.
- To elucidate the structures of isolated compounds using spectroscopic methods.
Main Methods:
- Liquid culture of Strobilurus stephanocystis.
- Extraction and isolation of fungal metabolites.
- Structure elucidation using spectroscopic techniques (e.g., NMR, MS).
Main Results:
- A new sesquiterpenoid, named strobiluric acid, was isolated.
- Seven known sesquiterpenoids were co-isolated with the new compound.
- The structures of all isolated compounds were confirmed through comprehensive spectroscopic analysis.
Conclusions:
- The chemical investigation of Strobilurus stephanocystis led to the discovery of a new sesquiterpenoid.
- This study expands the knowledge of secondary metabolites produced by this fungal species.
More Related Videos
Related Concept Videos
01:26Bacterial Phylum Planctomycetes
Planctomycetes are a group of morphologically distinct bacteria predominantly classified into two orders: Planctomycetales and Brocadiales. These gram-negative bacteria exhibit unique features, including division by budding and the presence of stalks or appendages. Their cells are often found in rosette arrangements, and they are notable for possessing an S-layer in their cell envelope, which is relatively uncommon among bacteria. Additionally, Planctomycetes frequently exhibit intracellular...
01:30Bacterial Phylum Spirochaetes
Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased by a...
01:15Drugs that Stabilize Microtubules
Microtubules are dynamic structures that undergo cycles of catastrophe and rescue. The microtubules play a central role in cell division by forming the spindle apparatus for segregating the chromosomes. This makes them ideal targets for regulating dividing cells in tumors and malignant cancer cells. Microtubule stabilizing drugs help stabilize the microtubule formation and promote its polymerization. Paclitaxel was the first microtubule stabilizing agent used as anticancer drug in chemotherapy...
02:33Stereoisomerism of Cyclic Compounds
In this lesson, we delve into the role of ring conformation and its stability, which determines the spatial arrangement and, consequently, the molecular symmetry and stereoisomerism of cyclic compounds. 1,2-Dimethylcyclohexane is used as a case study to evaluate the possible number of stereoisomers. Here, given the multiple (n = 2) chiral centers, there are 2n = 4 possible configurations that lack a plane of symmetry, as the ring skeleton exists in a non-planar chair conformation. In addition,...
02:26Non-vascular Seedless Plants
The diverse plant life on Earth—consisting of nearly 400,000 species—can be divided into three broad categories based on biological characteristics: nonvascular, seedless vascular, and seed plants.
01:30Bacterial Phylum Actinobacteria
Coryneform bacteria are gram-positive, aerobic, nonmotile rods that exhibit irregular, club-shaped, or V-shaped arrangements. Their V-shape results from snapping division, where the inner cell wall layer forms the cross-wall, while the outer layer remains intact until it ruptures on one side, causing the daughter cells to bend away.The primary genera are Corynebacterium and Arthrobacter. Corynebacterium includes diverse species, ranging from saprophytes to pathogens like Corynebacterium...