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Updated: Sep 29, 2026

Instrumentation of Near-term Fetal Sheep for Multivariate Chronic Non-anesthetized Recordings
Published on: October 25, 2015
[General anesthesia using calypsol during angiographic study of the extremities in children]
Abstract:
In 17 children aged 7 to 14 years angiography of the extremities (AGE) was performed under general anesthesia by intravenous calypsol injection without premedication with cholinolytics (group I, monoanesthesia) or with premedication with atropine and neuroleptics (diazepam, droperidol; group II). It has been established that calypsol, in both groups, had a short-term moderate stimulating effect on the cardiac function and an insignificant effect on the respiratory function, which was not essential for the assessment of hemodynamic parameters during AGE. Muscle relaxation was more marked in children of group II, mainly due to the use of neuroleptics. In children of group II muscle relaxation was insignificant, this was associated with certain difficulties during AG. A technique of calypsol anesthesia during AGE in children has been elaborated, it is recommended to use calypsol in combination with neuroleptics, and to strengthen anesthesia by additional calypsol administration prior to the injection of contrast agents.
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