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Updated: Jul 3, 2026

Hyperglycemic Clamp and Hypoglycemic Clamp in Conscious Mice
Published on: January 26, 2024
[Hypoglycemia and diabetes]
1Service de diabétologie, endocrinologie et nutrition, HUG, 1211 Genève 14. sheila.ardigo@hcuge.ch
Abstract:
Hypoglycaemia represents the limiting factor to obtain good glycemic control. Dysregulation of counteracting mechanisms and autonomic nervous system neuropathy contribute a strong increase in the incidence of hypoglycaemia in type 1 diabetic patients, but also in long lasting type 2 diabetic patients. Hypoglycaemia in elderly poses a diagnostic and clinical challenge of the unsual clinical presentation causing a delay in treatment. Treatment however, is simple and follows early detection of symptoms by the patient and his family. Prevention has a major role and involves identification of individual risk factors for hypoglycaemia and patient's education with the objective of adapting treatment to the usual habits of the patient.
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