Related Experiment Video
Updated: Jul 3, 2026

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice
Published on: May 2, 2025
[Examination of the kidneys in a diabetic patient]
1Klinika nefrologie 1. lékarské fakulty UK a VFN Praha. vladimir.tesar@lf1.cuni.cz
Abstract:
Diabetic nephropathy is the most frequent cause of terminal renal failure in the Czech Republic today. Diabetic patients should be screened for diabetic kidney disease on an annual basis, starting 5 years after diabetes was diagnosed in type 1 diabetes patients and immediately after diagnosis in type 2 diabetes patients. The screening includes determining the albumin/creatinine ratio from a urine sample, and of serum creatinine, and the calculation ofglomerular filtration rate. In patients in whom microalbuminuria and/or proteinuria were found, measures should be taken to reduce cardiovascular risk and to slow down the progression of renal disease. In diabetic patients with abnormal urine test results detailed nephrology examination is necessary to exclude other renal diseases than diabetic nephropathy, especially chronic glomerulonephritis and ischaemic nephropathy.
Related Concept Videos
Diabetic Nephropathy
Urine Studies I: Urinalysis
Nursing Assessment of the Genitourinary System II: Inspection and Palpation
Diabetes: Symptoms, Diagnosis, and Complications
Imaging Studies VII: Vascular Imaging
Chronic Kidney Disease III: Interprofessional Care
