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Published on: June 7, 2012
[Effects of different intensity pulsed electromagnetic fields on serum estradiol of ovariectomized rats]
Yong-Hong Yang1, Cheng-Qia He, Lin Yang
1Department of Rehabilitation, West China Hospital, Sichuan University, Chengdu 610041, China.
Objective:
To explore the effects of different intensity pulsed electromagnetic fields (PEMFs) on serum estradiol in ovariectomized rats.
Methods:
Fifty female SD rats were randomly divided into five groups: sham-operated control (no PEMF treatment), ovariectomized control(no PEMF treatment),ovariectomized group I, II, III (PEMF treatment at 8 Hz frequency and 0.77 mT, 3.82 mT, 9.87 mT intensity, 40 min daily for 30 days). Except for the sham-operated control rats, a standardized ovariectomy was used on every rat of other groups. The serum estradiol(E2) of rats was assessed at 30 days after PEMF treatment.
Results:
The E2 values of the SHAM control group were significantly higher than those of other four groups (P < 0.05 or P < 0.01), but the difference in E2 values was not significant among the other four groups (P > 0.05).
Conclusion:
PEMFs can not improve the serum estradiol level of ovariectomized rat, it shows that the therapeutical effect of PEMFs is not due to improve the serum estradiol level.
