Related Experiment Video
Updated: Jul 3, 2026

12:29
mRNA Interactome Capture from Plant Protoplasts
Published on: July 28, 2017
Regulation of flowering time by RNA processing.
1Scottish Crop Research Institute, Invergowrie, UK.
Current Topics in Microbiology and Immunology
|July 18, 2008
Summary
Plants precisely control flowering time using environmental signals and internal development. This review highlights RNA processing, including splicing and miRNA biogenesis, as key regulators of flowering time in plants.
Area of Science:
- Plant Biology
- Molecular Biology
- Genetics
Background:
- Flowering time is a crucial quantitative trait in plants, influenced by environmental cues and developmental programs.
- It serves as a model for understanding precise gene regulation.
- RNA processing plays a significant role in gene regulation, but its specific impact on flowering time requires further elucidation.
Purpose of the Study:
- To review the role of RNA processing-based gene regulatory phenomena in controlling plant flowering time.
- To discuss conserved RNA processing events and novel plant-specific regulators affecting flowering time.
- To present new approaches for dissecting the mechanisms of flowering time control.
Main Methods:
- Literature review of conserved and plant-specific RNA processing mechanisms.
- Analysis of RNA-binding proteins involved in flowering time regulation.
- Integration of information on alternative pre-mRNA processing in flowering time pathways.
Main Results:
- Flowering time control is significantly influenced by RNA processing events, including alternative 3' end formation, splicing, RNA export, and miRNA biogenesis.
- Novel plant-specific RNA-binding proteins have been identified as crucial regulators of flowering time.
- Alternative processing of flowering time gene pre-mRNAs contributes to the regulatory network.
Conclusions:
- RNA processing is a central mechanism in the precise control of plant flowering time.
- Understanding these RNA-based regulatory mechanisms offers new avenues for crop improvement and dissecting developmental processes.
More Related Videos
Related Concept Videos
Regulation of Expression at Multiple Steps
The gene expression in cells is regulated at different stages: (i) transcription, (ii) RNA processing, (iii) RNA localization, and (iv) translation. Transcriptional regulation is mediated by regulatory proteins such as transcription factors, activators, or repressors—these control gene expression by initiating or inhibiting the transcription of genes. Once a precursor or pre-mRNA is produced, it undergoes post-transcriptional modification, including 5' capping, splicing, and the addition of a...
Regulation of Expression Occurs at Multiple Steps
Gene expression can be regulated at almost every step from gene to protein. Transcription is the step that is most commonly regulated. This involves the binding of proteins to short regulatory sequences on the DNA. This association can either promote or inhibit the transcription of a gene associated with the respective sequence.
Transcription results in the generation of precursor (pre-mRNA) that consists of both exons and introns, which needs further processing before being translated to a...
Transcription results in the generation of precursor (pre-mRNA) that consists of both exons and introns, which needs further processing before being translated to a...
Regulation of Expression Occurs at Multiple Steps
Gene expression can be regulated at almost every step from gene to protein. Transcription is the step that is most commonly regulated. This involves the binding of proteins to short regulatory sequences on the DNA. This association can either promote or inhibit the transcription of a gene associated with the respective sequence.
Transcription results in the generation of precursor (pre-mRNA) that consists of both exons and introns, which needs further processing before being translated to a...
Transcription results in the generation of precursor (pre-mRNA) that consists of both exons and introns, which needs further processing before being translated to a...
Transcriptional Regulation: Riboswitches
Riboswitches are RNA elements that regulate gene expression by altering their secondary structures in response to specific effector molecules. These elements, located in the leader regions of certain mRNAs, act as transcriptional regulators by toggling between alternative conformations to control downstream gene expression. Riboswitch-mediated regulation is a precise mechanism for modulating biosynthetic pathways, as exemplified by the riboflavin biosynthesis pathway in Bacillus...
Chromatin Structure Regulates pre-mRNA Processing
In eukaryotic cells, nascent mRNA transcripts need to undergo many post-transcriptional modifications to reach the cell cytoplasm and translate into functional proteins. For a long time, transcription and pre-mRNA processing were considered two independent events that occur sequentially in the cell. However, it has now been well established that transcription and pre-mRNA processing are two simultaneous processes that are precisely regulated inside the cell.
The chromatin structure, especially...
The chromatin structure, especially...
Translational Regulation
Translational regulation in prokaryotes ensures efficient protein synthesis by controlling ribosome access to mRNA. This regulation is mediated by secondary RNA structures, including translational riboswitches, RNA thermometers, and small RNAs (sRNAs), which respond to intracellular and environmental signals to modulate gene expression.Translational RiboswitchesRiboswitches in the leader region of mRNAs can regulate translation by altering the accessibility of the Shine-Dalgarno (SD) sequence,...

