Related Experiment Video

Updated: Jul 3, 2026

Chemical Reversion of Conventional Human Pluripotent Stem Cells to a Naïve-like State with Improved Multilineage Differentiation Potency
09:07

Chemical Reversion of Conventional Human Pluripotent Stem Cells to a Naïve-like State with Improved Multilineage Differentiation Potency

Published on: June 10, 2018

Alternative sources of pluripotency: science, ethics, and stem cells

Zachary J Kastenberg1, Jon S Odorico

  • 1Division of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health and WiCell Research Institute, Madison, WI 53792, USA.

Transplantation Reviews (Orlando, Fla.)
|July 18, 2008
PubMed

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Stem cells are undifferentiated cells that divide and produce different cell types. Ordinarily, cells that have differentiated into a specific cell type are terminally differentiated; however, scientists have found a way to reprogram these mature cells so that they dedifferentiate and return to an unspecialized, proliferative state. These cells are pluripotent like embryonic stem cells—able to produce all cell types—and are called induced pluripotent stem cells (iPSCs).
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