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Coronary artery stents: II. Perioperative considerations and management
Lisa T Newsome1, Robert S Weller, J C Gerancher
1Department of Anesthesiology, Wake Forest University School of Medicine, Winston-Salem, NC 27157-1009, USA. LTN723@triad.rr.com
Insights
Managing patients with coronary artery stents during surgery requires careful planning to prevent stent thrombosis. Continuing aspirin is crucial, with immediate intervention for thrombosis saving lives.
Area of Science:
- Cardiology
- Perioperative Medicine
- Interventional Cardiology
Background:
- Perioperative management of patients with coronary artery stents is a critical patient safety concern.
- Stent thrombosis, myocardial infarction, and death are life-threatening risks, especially after non-cardiac surgery early post-implantation.
- Discontinuing dual-antiplatelet therapy preoperatively significantly increases complication rates.
Purpose of the Study:
- To outline strategies for managing patients with coronary artery stents during the perioperative period.
- To provide recommendations for regional anesthesia and postoperative care to mitigate risks.
- To propose algorithms for the management of bare-metal and drug-eluting stents.
Main Methods:
- Review of current literature and clinical guidelines.
- Consideration of risk factors for perioperative stent thrombosis.
- Development of management algorithms based on stent type and procedural risk.
Main Results:
- Aspirin continuation is generally recommended throughout the perioperative period, balancing bleeding risk.
- The postoperative period presents the highest risk for perioperative stent thrombosis.
- Immediate percutaneous coronary intervention is the definitive treatment for stent thrombosis.
Conclusions:
- Perioperative management protocols are essential for patient safety in those with coronary stents.
- Algorithms aid clinicians in making informed decisions regarding antiplatelet therapy and surgical timing.
- Readily available 24-h interventional cardiology services are vital for managing emergent stent thrombosis.
Abstract:
The management of patients with coronary artery stents during the perioperative period is one of the most important patient safety issues clinicians confront. Perioperative stent thrombosis is a life-threatening complication for patients with either bare-metal or drug-eluting stents. Noncardiac surgery appears to increase the risk of stent thrombosis, myocardial infarction, and death, particularly when patients undergo surgery early after stent implantation. The incidence of complications is further increased when dual-antiplatelet therapy is discontinued preoperatively. It is generally agreed that aspirin must be continued throughout the perioperative period, except in circumstances when the risk of bleeding significantly outweighs the benefit of continued anticoagulation, such as procedures performed in a closed space. We present considerations for regional anesthesia, as well as postoperative recommendations as the occurrence of perioperative stent thrombosis appears to be greatest during this period. Immediate percutaneous coronary intervention is the definitive treatment for perioperative stent thrombosis, and 24-h access to an interventional cardiology suite should be readily available. Algorithms for perioperative management of patients with bare-metal and drug-eluting stents are proposed.
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