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Updated: Jul 3, 2026

A Doxorubicin-Induced Murine Model of Dilated Cardiomyopathy In Vivo
Published on: May 16, 2020
[A long-term survivor after relapsed acute myeloblastic leukemia with anthracycline dilated cardiomyopathy]
Yoshiko Saito1, Sakura Ishikawa, Hiromi Endo
1Miyagigakuin Women's University.
Abstract:
We watched and analyzed patient cardiac functions especially with a "Phased tracking method" to detect rapid motion of the heart. The patient suffered from congestive heart failure while depending on anthracycline cumulative doses, but now has been living more than 10 years after relapsed acute myeloblastic leukemia. To avoid congestive heart failure with increasing highly tumoricidal anthracycline doses, cardiac function should be monitored closely in connection with treatment schedules and proposed accurate therapeutic index.
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