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Related Concept Videos

Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term proteomics...
Urine Studies I: Urinalysis01:29

Urine Studies I: Urinalysis

Urinalysis is a widely used diagnostic test that analyzes urine's physical, chemical, and microscopic characteristics. Healthcare providers use it to detect and monitor various health conditions, including renal disease, urinary tract infections (UTIs), diabetes, and metabolic or systemic disorders.Components of UrinalysisUrinalysis consists of three primary components: physical, chemical, and microscopic examination. Each provides unique insights into the urine sample and, by extension, the...
Microbiota of the Urogenital Tract01:28

Microbiota of the Urogenital Tract

The human urogenital system, once thought to be sterile in healthy individuals, is now recognized as a complex microbial habitat. Advancements in molecular sequencing techniques have revealed that even in healthy adults, the kidneys and bladder harbor microbial populations similar to those found in the distal urethra, albeit in much lower abundance. These resident microorganisms, while generally innocuous, can become opportunistic pathogens under conditions that alter the urogenital...
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...

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Related Experiment Video

Updated: Jul 3, 2026

Proteomic Profile of EPS-Urine through FASP Digestion and Data-Independent Analysis
14:48

Proteomic Profile of EPS-Urine through FASP Digestion and Data-Independent Analysis

Published on: May 8, 2021

Urinary proteomics: towards biomarker discovery, diagnostics and prognostics.

Visith Thongboonkerd1

  • 1Faculty of Medicine Siriraj Hospital, Medical Proteomics Unit & Medical Molecular Biology Unit, Office for Research and Development, Mahidol University, Bangkok, Thailand. thongboonkerd@dr.com

Molecular Biosystems
|July 18, 2008
PubMed
Summary

Urinary proteomics offers a non-invasive approach for disease biomarker discovery and diagnostics. Recent advancements highlight its growing clinical applications for improved patient health outcomes.

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CRISPR-Cas-mediated Multianalyte Synthetic Urine Biomarker Test for Portable Diagnostics

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Last Updated: Jul 3, 2026

Proteomic Profile of EPS-Urine through FASP Digestion and Data-Independent Analysis
14:48

Proteomic Profile of EPS-Urine through FASP Digestion and Data-Independent Analysis

Published on: May 8, 2021

CRISPR-Cas-mediated Multianalyte Synthetic Urine Biomarker Test for Portable Diagnostics
04:33

CRISPR-Cas-mediated Multianalyte Synthetic Urine Biomarker Test for Portable Diagnostics

Published on: December 8, 2023

Area of Science:

  • Clinical Proteomics
  • Biomedical Science

Background:

  • Proteomics is increasingly applied in clinical settings for disease biomarker discovery, diagnostics, and prognostics.
  • Urine is an ideal clinical sample due to its non-invasive collection and wide availability.
  • Urinary proteomics is a rapidly developing subdiscipline within clinical proteomics.

Purpose of the Study:

  • To highlight and update recent progress in urinary proteomics.
  • To emphasize the clinical applications of urinary proteomics.

Main Methods:

  • Review of recent advancements in urinary proteomics techniques.
  • Analysis of studies focusing on clinical applications of urinary proteomics.

Main Results:

  • Significant progress has been made in urinary proteomics for clinical applications.
  • Urinary proteomics shows promise for biomarker discovery, diagnostics, and prognostics.

Conclusions:

  • Urinary proteomics is a valuable tool for clinical applications.
  • Continued research in urinary proteomics will enhance disease diagnosis and patient management.