Night-time cough in children with acute wheezing and with upper respiratory tract infection

Jacob Urkin1, Yaron Ishay, Natalya Bilenko

  • 1Division of Community Health, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel. medcad@bgu.ac.il

Insights

Night-time cough patterns in children with acute wheezing (AW) differ significantly from those with an upper respiratory tract infection (URTI). This distinction can aid in clinical diagnosis of pediatric respiratory conditions.

Area of Science:

  • Pediatric Pulmonology
  • Sleep Medicine
  • Diagnostic Tools

Background:

  • Nocturnal cough is a common symptom in children.
  • Differentiating causes like acute wheezing and upper respiratory tract infections (URTIs) can be challenging.
  • Objective cough monitoring may provide valuable diagnostic insights.

Purpose of the Study:

  • To analyze and compare night-time cough characteristics in children diagnosed with acute wheezing versus URTI.
  • To determine if objective cough data can correlate with clinical diagnoses.

Main Methods:

  • A portable cough monitoring instrument was used to record night-time coughs in 49 children.
  • Children were diagnosed with either acute wheezing or URTI.
  • Cough variables including frequency, duration, and bout patterns were analyzed.

Main Results:

  • Children with acute wheezing exhibited significantly higher cough frequency, longer cough durations, and more frequent coughing bouts per night compared to URTI cases.
  • Peak coughing activity for acute wheezing occurred between 23:00 and 01:00.
  • No significant difference in cough counts was observed between groups from 01:00 to 06:00.

Conclusions:

  • Distinct quantitative differences in night-time cough patterns exist between acute wheezing and URTI in children.
  • Objective cough monitoring shows potential as a supplementary tool for clinical differentiation in pediatric respiratory illness.
Abstract

Related Concept Videos

Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
Pulmonary Cycle: Exhalation01:17

Pulmonary Cycle: Exhalation

In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics01:23

Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics

Respiratory symptoms, such as congestion and cough, commonly accompany respiratory tract conditions. Various medications, such as antitussives, expectorants, and mucolytics, play crucial roles in providing relief.
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla.  Benzonatate operates peripherally within the respiratory tract by anesthetizing...
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Common Respiratory Disorders01:31

Common Respiratory Disorders

Respiratory disorders, a prevalent health concern globally, are generally divided into two primary categories: upper and lower respiratory tract disorders. The categorization is based on the area of the respiratory system they affect.
Upper respiratory disorders impact the airways above the vocal cords, encompassing areas like the nose, sinuses, and throat. Various conditions fall under this category, including the common cold and allergic rhinitis. These disorders can stem from several causes,...