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Mass screening for neuroblastoma in Japan
T Sawada1, T Sugimoto, H Kawakatsu
1Department of Pediatrics, Kyoto Prefectural University of Medicine, Japan.
Pediatric Hematology and Oncology
|April 1, 1991
Summary
Japan's pioneering neuroblastoma mass screening program, initiated in 1973, has successfully detected 337 early-stage cases. This national initiative, involving mothers and healthcare providers, anticipates a 97% cure rate, though challenges persist.
Area of Science:
- Pediatric Oncology
- Public Health Screening
- Cancer Epidemiology
Background:
- Neuroblastoma is a significant childhood cancer.
- Early detection is crucial for improving patient outcomes.
- Japan launched the world's first national neuroblastoma mass screening program in 1973.
Purpose of the Study:
- To evaluate the status and effectiveness of Japan's national neuroblastoma mass screening program.
- To analyze the outcomes of neuroblastoma cases detected through mass screening.
- To identify remaining challenges in the program's implementation and operation.
Main Methods:
- The study evaluated a national mass screening program conducted from 1973 to 1989.
- Data included 337 neuroblastoma cases detected and analyzed.
- Collaboration involved mothers, local health centers, screening centers, and hospitals.
Main Results:
- 337 neuroblastoma cases were detected and analyzed between 1973 and 1989.
- The majority of detected cases were in early stages.
- An expected cure rate of 97% was reported for detected cases.
Conclusions:
- The neuroblastoma mass screening program in Japan has demonstrated high success in early detection and expected cure rates.
- The program's collaborative approach involving mothers and healthcare professionals was integral to its operation.
- Unresolved social, technical, and clinical issues require further attention for program optimization.