Related Experiment Video
Updated: Jul 3, 2026

Acquisition of Resting-State Functional Magnetic Resonance Imaging Data in the Rat
Published on: August 28, 2021
The efficacy of dexmedetomidine in patients with noninvasive ventilation: a preliminary study
Shinji Akada1, Shinhiro Takeda, Yuko Yoshida
1Department of Anesthesiology and Intensive Care, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan.
Background:
Agitation is associated with failure of noninvasive ventilation (NIV). We investigated the effect of dexmedetomidine in patients with NIV.
Methods:
This was a prospective clinical investigation in an intensive care unit. Dexmedetomidine was infused in 10 patients in whom NIV was difficult because of agitation.
Results:
Ramsay and Richmond Agitation-Sedation Scale scores were maintained at 2.94 +/- 0.94 and -1.23 +/- 1.30, respectively. All patients were successfully weaned from NIV, and the respiratory state was not worsened.
Conclusion:
This study shows that dexmedetomidine is an effective sedative drug for patients with NIV.
Related Concept Videos
Parenteral Anesthetics: Overview
Depolarizing Blockers: Pharmocokinetics
Mechanical Ventilation III: Noninvasive Ventilation
Noninvasive Positive-Pressure Ventilation (NIPPV)
Skeletal Muscle Relaxants: Adverse Effects
Unlike...
Skeletal Muscle Relaxants: Therapeutic Uses
