Status epilepticus and intrathecal fluorescein: anesthesia providers beware

Fluorescein is a fluorochrome dye occasionally administered by intrathecal injection to identify and localize cerebrospinal fluid leaks. Although generally considered to be a benign intervention, intrathecal administration of fluorescein has resulted in adverse events. We report a case of status epilepticus after intrathecal administration of fluorescein. Anesthesia providers should be aware of complications associated with intrathecal fluorescein use and be prepared to manage neurologic complications during the perioperative period.