Feasibility of intraoperative aortic root angiography in the identification of critical coronary lesions

Early revascularization is critical for the treatment of acute myocardial infarction (AMI) because the ischemic myocardium begins to suffer irreversible damage after 4 h from the onset of symptoms. However, to make a diagnosis, perform coronary angiography, and prepare for operative revascularization usually takes longer than 4 h. Also, once a patient develops severe cardiogenic shock, coronary angiography is often impossible. Without angiography, the patient is no longer a candidate for surgical repair. To circumvent this problem, we designed this experiment to determine whether intraoperative aortic root angiography after cardiopulmonary bypass and cardioplegic arrest could satisfactorily substitute for angiographic examination in the identification of critical coronary lesions. The feasibility of this approach was tested in dog hearts in which one or tow of the major coronary arteries were ligated. The ascending aorta was then clamped, contrast material was injected, and continuous real-time fluoroscopic images were obtained and recorded on videotape. The videotape was then analyzed by three physicians independently, each without prior knowledge of the lesion locations. Lesions of the left anterior descending artery, the circumflex coronary artery, and the right coronary artery were identified with 94, 91, and 94% accuracy, respectively, for an overall identification rate of 92%. We conclude that aortic root angiography reliably demonstrates coronary artery lesions, and refinements in this technique may allow certain patients to undergo coronary operations without preoperative catheterization.