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Updated: Jul 3, 2026
Genome-Wide Analysis of DNA Methylation in Gastrointestinal Cancer
Published on: September 18, 2020
[Clinical analysis of 98 cases of primary gastric lymphoma]
Hai-Tao Zhou1, Zhi-Xiang Zhou, Hai-Zen Zhang
1Department of Abdominal Surgery, Cancer Hospital, Chinese Academy of Medical Science, Peking Union Medical College, Beijing, China. zhouzx01@yahoo.com.cn
Objective:
To explore the clinical characteristics, diagnosis and treatment regimens for the primary gastric lymphoma (PGL).
Methods:
The data of 98 PGL patients treated from January 1994 to December 2006 were collected and analyzed retrospectively.
Results:
Abdominal pain was the common symptom of PGL. All the patients were at stage I or stage II, and the preoperative diagnosis rate was 56.5%. The overall 1-, 3- and 5-year survival rates were 95.1%, 86.0% and 73.0% respectively. The 5-year survival rates of stage I and stage II patients were 89.5% and 66.7% respectively, and the difference was significant. The 5-year survival rate of patients received operations was 77.2% and that without operation was 75.0%, the difference was not significant.
Conclusions:
The therapy based on chemotherapy is preferred for the treatment of PGL. In the cases of serious gastrointestinal complications, indefinite pathological diagnosis or non-effective chemotherapy, operations should be considered.
