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Updated: Jul 3, 2026

Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae

Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae

Published on: February 24, 2023

Comamonas testosteroni meningitis in a homeless man.

Long Jin¹, Joshua A Perper, Stephen J Cina

¹Broward County Medical Examiner's Office, Fort Lauderdale, FL 33312, USA.

Journal of Forensic Sciences

|July 22, 2008

Summary

This case report details the first fatal meningitis caused by Comamonas testosteroni, a bacterium typically found in soil and water. The infection occurred in a trauma patient with a severe facial bone fracture.

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Last Updated: Jul 3, 2026

Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae

Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae

Published on: February 24, 2023

Area of Science:

Infectious Diseases
Neurology
Microbiology

Background:

Comamonas testosteroni is a Gram-negative bacterium commonly found in environmental sources like soil and water.
Meningitis is a serious infection of the membranes surrounding the brain and spinal cord.

Observation:

A 54-year-old male with a history of alcoholism and homelessness sustained severe facial bone fractures after a car accident.
The patient developed cerebral and cerebellar infarcts, altered mental status, and was diagnosed with meningitis.
Autopsy revealed diffuse purulent meningitis, with cultures positive for Comamonas testosteroni.

Findings:

This is the first documented case of fatal meningitis attributed to Comamonas testosteroni.
The organism, typically non-pathogenic to humans, may have gained access to the central nervous system through the facial bone fractures.

Implications:

Highlights the potential for environmental bacteria to cause opportunistic infections in severely compromised hosts.
Suggests Comamonas testosteroni should be considered in the differential diagnosis of meningitis, especially in patients with relevant exposure or trauma.
Underscores the importance of considering unusual pathogens in severe infections following significant trauma.