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Opioids for nonmalignant pain.

Warren A Katz1

  • 1University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

Rheumatic Diseases Clinics of North America
|July 22, 2008
PubMed
Summary
This summary is machine-generated.

Opioids can be a safe and effective treatment for chronic nonmalignant pain when risks are managed. Long-acting opioids are a consideration for patients with persistent rheumatic pain unresponsive to other therapies.

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Area of Science:

  • Pain Management
  • Pharmacology
  • Rheumatology

Background:

  • Pain is a leading global health concern driving patient consultations.
  • Opioid therapy presents a viable option for specific chronic nonmalignant pain cases.
  • Managing opioid risks like abuse and side effects is often feasible.

Purpose of the Study:

  • To evaluate the role of opioids in managing chronic nonmalignant pain.
  • To assess the risk-benefit profile of opioid use in this patient population.
  • To provide guidance on opioid consideration for refractory rheumatic pain.

Main Methods:

  • Review of existing literature on opioid efficacy and safety in chronic pain.
  • Analysis of risk factors and mitigation strategies for opioid therapy.
  • Consideration of long-acting opioids for treatment-resistant rheumatic conditions.

Main Results:

  • Opioid risks, including abuse and side effects, are generally manageable.
  • Opioids are not universally suitable for all chronic nonmalignant pain patients.
  • Long-acting opioids warrant consideration for patients with persistent rheumatic pain after other treatments fail.

Conclusions:

  • Opioid therapy requires careful patient-specific risk-benefit assessment.
  • Untreated severe chronic pain carries significant morbidity and mortality risks.
  • Strategic use of opioids can improve outcomes for select chronic pain patients.