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Updated: Jul 3, 2026

Optimizing Minimally Invasive Spine Surgery: A Fully 3D CT O-Arm Navigated Workflow in MIS TLIF
Published on: October 17, 2025
Frameless stereotaxis for the insertion of lumbar pedicle screws
M A Murphy1, R L McKenzie, D W Kormos
1Department of Neurosurgery, The Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Abstract:
Spinal instrumentation and frameless stereotaxy are two separate fields in neurosurgery that have rapidly advanced in recent years. The application of stereotaxis to spinal surgery has previously been limited by the inaccuracy of surface mounted reference points. The development of frameless stereotaxy using anatomical registration techniques has overcome this problem and has allowed stereotactic techniques to be successfully applied to spinal surgery at our institution. We tested our frameless spinal stereotactic technique in cadaver studies with optimal screw placement. The technique is currently undergoing preliminary clinical evaluation. We review the technique and its application to spinal instrumentation.

