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Related Experiment Videos

Olive pollen induces asthmatic response.

R Tamir1, A I Pick, M Topilsky

  • 1Division of Clinical Immunology and Allergy, Beilinson Medical Centre, Petah Tikva, Israel.

Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology
|May 1, 1991
PubMed
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Olive pollen extract can trigger asthma responses in sensitive individuals. This study found that olive pollen can cause both early and dual asthmatic responses in patients with allergic rhinitis and asthma.

Area of Science:

  • Allergology
  • Pulmonology
  • Immunology

Background:

  • Seasonal allergic rhinitis and asthma are common conditions.
  • Olive pollen is a known allergen, but its specific role in inducing asthmatic responses requires further investigation.
  • Understanding the pattern of airway response to allergens like olive pollen is crucial for effective management.

Purpose of the Study:

  • To investigate the pattern of airway response to olive pollen extract in patients with suspected olive pollen allergy.
  • To determine if olive pollen can induce early asthmatic response (EAR) and/or dual asthmatic response (DAR).

Main Methods:

  • Nineteen patients with allergic rhinitis and asthma, confirmed positive for olive pollen allergy via skin-prick tests, were enrolled.
  • Bronchial challenge tests were performed using olive pollen extract.

Related Experiment Videos

  • Peak expiratory flow rate was monitored for 20 hours to assess asthmatic responses.

    • Main Results:

    • Eight patients (42%) exhibited dual asthmatic response (DAR).
    • Six patients (32%) showed early asthmatic response (EAR) only.
    • Five patients (26%) had no significant asthmatic response.
    • No significant difference was found in the early maximal fall in FEV1 or PD15 between patients with DAR and EAR only.

    Conclusions:

    • Olive pollen extract can induce asthmatic responses in susceptible individuals.
    • Dual asthmatic response (DAR) is a potential outcome of olive pollen exposure.
    • Further research may elucidate the mechanisms underlying DAR to olive pollen.