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Cranial and Spinal Meninges

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Cranial Meninges
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Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
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Published on: July 5, 2021

Intracranial chondroid chordoma.

T Akai1, M Sonobe, K Sugita

  • 1Department of Neurosurgery, Mito National Hospital, 3-2-1 Higashihara Mito Ibaraki 310, Japan.

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
|April 1, 1997
PubMed
Summary

This case study details a rare chondroid chordoma causing oculomotor nerve palsy. Surgical removal of the parasellar tumor resolved symptoms, with later hemorrhage in the prepontine tumor requiring further intervention.

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Area of Science:

  • Neurosurgery
  • Oncology
  • Pathology

Background:

  • Chordomas are rare tumors originating from notochord remnants.
  • Chondroid chordoma is considered a variant of chordoma.
  • These tumors can present with diverse neurological symptoms.

Purpose of the Study:

  • To report a case of chondroid chordoma presenting with oculomotor nerve palsy.
  • To describe the diagnostic imaging and surgical management of this rare tumor.
  • To highlight the distinct radiological features and histological evolution of the tumor.

Main Methods:

  • Clinical presentation of a patient with a parasellar and prepontine mass.
  • Diagnostic imaging using Computed Tomography (CT) and Magnetic Resonance Imaging (MRI).
  • Surgical resection of the parasellar tumor followed by resection of the prepontine tumor after hemorrhage.

Main Results:

  • The parasellar tumor removal led to the resolution of oculomotor nerve palsy.
  • Histological examination confirmed chondroid chordoma in the resected parasellar mass.
  • Subsequent hemorrhage in the prepontine tumor revealed a composition of pure chordoma tissue upon resection.

Conclusions:

  • Chondroid chordoma can manifest with cranial nerve deficits.
  • Distinct enhancement patterns on CT can differentiate co-existing tumor components.
  • Surgical intervention is crucial for managing symptomatic chordomas, with potential for histological changes over time.