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Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
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A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
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A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
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Related Experiment Video

Updated: Jul 3, 2026

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
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Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model

Published on: June 18, 2021

Infected subdural hematoma.

S Sawauchi1, T Saguchi, Y Miyazaki

  • 1Department of Neurosurgery, The Jikei University School of Medicine, 3-25-8 Nishi-Shinbashi, Minatoku, Tokyo 105, Japan.

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
|July 22, 2008
PubMed
Summary

Infection can seed chronic subdural hematomas, with Escherichia coli being a common cause, often originating from urinary tract infections. This case highlights the importance of considering infected subdural hematoma in patients with relevant symptoms.

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Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage
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Published on: August 30, 2020

Related Experiment Videos

Last Updated: Jul 3, 2026

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
09:14

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model

Published on: June 18, 2021

Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage
10:34

Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage

Published on: August 30, 2020

Area of Science:

  • Neurology
  • Infectious Diseases
  • Neurosurgery

Background:

  • Chronic subdural hematomas (CSDH) are collections of blood over the brain's surface.
  • Infection of CSDH is rare but can lead to severe neurological complications.
  • Escherichia coli is a frequent pathogen in spontaneous bacterial infections.

Purpose of the Study:

  • To report a case of a chronic subdural hematoma infected by Escherichia coli.
  • To discuss the potential source of infection and clinical presentation.
  • To emphasize the diagnostic considerations for infected subdural hematoma.

Main Methods:

  • Case presentation of a 77-year-old female with lethargy, hemiparesis, and fever.
  • Diagnosis of bilateral chronic subdural hematoma via computed tomography.
  • Surgical drainage via burr hole and microbiological analysis of hematoma fluid.

Main Results:

  • Operative findings confirmed an infected right-sided subdural hematoma and a non-infected left-sided hematoma.
  • Cultures of the infected hematoma yielded Escherichia coli.
  • Pyuria suggested a urinary tract infection as the likely source of the hematoma infection.

Conclusions:

  • Infected chronic subdural hematoma should be suspected in patients presenting with signs of infection and CT findings suggestive of CSDH.
  • Urinary tract infections are a potential source for Escherichia coli seeding of subdural hematomas.
  • Prompt diagnosis and treatment are crucial for favorable outcomes in infected subdural hematoma cases.