Related Experiment Video
Updated: Jul 3, 2026

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice
Published on: December 27, 2024
Treatment of an intracranial germinoma spinal metastasis
1Kenneth Jamieson Unit, Department of Neurosurgery, Royal Brisbane Hospital, Brisbane, Australia.
Abstract:
A 20-year-old male with a solitary intradural extramedullary spinal metastasis from a pineal germinoma presented with progressive spinal cord compression. This was initially treated with radiotherapy and the patient showed rapid clinical improvement with complete resolution of his neurological symptoms and signs. Subsequent systemic chemotherapy resulted in complete radiological resolution of the lesion. This case is presented to demonstrate radiotherapy and chemotherapy as a treatment option for germinoma 'drop' metastasis causing spinal cord compression, along with a review of the literature.
