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Updated: Jul 3, 2026

Multimodality Diagnosis of Mesenteric Ischemia

Multimodality Diagnosis of Mesenteric Ischemia

Published on: July 21, 2023

Mesenteric Castleman disease.

Ke Ren Zhang¹, Hui Min Jia

¹Department of Pediatric Surgery, Shengjing Hospital, China Medical University, Liaoning 110004, PR China. zkr425@yahoo.com

Journal of Pediatric Surgery

|July 22, 2008

Summary

This summary is machine-generated.

Castleman disease, a rare benign lymph node hyperplasia, often presents as an asymptomatic mediastinal mass in children. While it can occur in various extrathoracic locations, mesenteric Castleman disease is exceptionally uncommon in pediatric patients.

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Last Updated: Jul 3, 2026

Multimodality Diagnosis of Mesenteric Ischemia

Multimodality Diagnosis of Mesenteric Ischemia

Published on: July 21, 2023

Area of Science:

Pediatric Oncology
Rare Diseases
Lymphoproliferative Disorders

Background:

Castleman disease (CD) is a rare lymphoproliferative disorder characterized by benign lymph node hyperplasia.
It typically manifests as an asymptomatic mediastinal mass in pediatric cases.
CD can arise in extrathoracic locations with lymphoid tissue, including the retroperitoneum, mesentery, axilla, and pelvis.

Observation:

This abstract focuses on the presentation of Castleman disease in children.
It highlights the common mediastinal location and the possibility of extrathoracic manifestations.
A specific emphasis is placed on the rarity of mesenteric Castleman disease in pediatric populations.

Findings:

Castleman disease is a rare benign lymph node hyperplasia.
Pediatric cases commonly present as asymptomatic mediastinal masses.
Extrathoracic presentations are possible, but mesenteric Castleman disease is particularly rare in children.

Implications:

Increased awareness of extrathoracic presentations of Castleman disease in children is warranted.
The rarity of mesenteric Castleman disease suggests unique etiological or developmental factors in pediatric cases.
Further research into the specific characteristics and management of rare pediatric Castleman disease presentations is needed.