Related Experiment Video
Updated: Jul 3, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Which obese children should have a sleep study?
S A McKenzie1, A Bhattacharya, R Sureshkumar
12nd floor, Fielden House, Royal London Hospital, Barts and the London NHS Trust, Whitechapel, London E1 1BB, UK. s.a.mckenzie@awell.co.uk
Insights
Identifying obstructive sleep apnoea (OSA) in obese children is crucial. Clinical features like reported apnoea, restless sleep, or tonsillar hypertrophy can effectively identify most children needing sleep studies.
Area of Science:
- Pediatric Endocrinology
- Sleep Medicine
- Public Health
Background:
- Childhood obesity is a growing concern, prompting UK government recommendations for specialized services.
- The prevalence of obesity presents challenges for widespread screening of obstructive sleep apnoea (OSA).
- Limited availability of pediatric sleep services necessitates efficient diagnostic strategies.
Purpose of the Study:
- To evaluate the predictive value of clinical features for significant OSA in obese children.
- To aid in prioritizing children for sleep studies and treatment.
- To develop a more targeted approach to diagnosing OSA in pediatric obesity.
Main Methods:
- A cohort of obese children (BMI >2.5 z scores) aged 2-16 years underwent sleep studies.
- Sleep studies included overnight oximetry and audiovisual recordings.
- Significant OSA was defined by oxygen desaturation events or respiratory-event related arousals.
Main Results:
- 26% of the 158 children studied had significant OSA.
- 95% of children with OSA presented with reported apnoea, restless sleep, or tonsillar hypertrophy.
- Body Mass Index (BMI) z scores did not correlate with OSA severity.
Conclusions:
- Screening obese children with reported apnoea, restless sleep, or tonsillar hypertrophy identifies 95% of those with significant OSA.
- This targeted approach can optimize the use of sleep study resources.
- Clinical assessment can effectively guide the need for further OSA investigation in obese children.
Background:
The UK government has recommended the development of obesity services for children. As obesity is common, studying every obese child for obstructive sleep apnoea (OSA) would be challenging and full paediatric sleep services are not available in every area in Europe. The purpose of this study was to consider how well clinical features predict significant OSA in obese children in order to help prioritise the need for sleep studies and subsequent treatment.
Methods:
Consecutive children referred for obesity management aged 2-16 years with a body mass index (BMI) of >2.5 z scores for age were offered a sleep study using overnight oximetry and audiovisual recordings. Significant OSA was defined as > or = 5 dips/h of >4% oxygen saturation or > or = 5 respiratory-event related arousals/h.
Results:
Forty-one of 158 (26%) children (mean BMI z score 3.7) had significant OSA and 95% of these had either reported apnoea, restless sleep or tonsillar hypertrophy (TH). Nineteen percent of all children had none of these features. BMI was not related to OSA.
Conclusion:
If only obese children with reported apnoea, restless sleep or TH have a sleep study, 95% of all obese children with significant OSA will be identified using this method.
Related Concept Videos
Sleep Apnea
The condition is more prevalent among...
Substance Use Disorders Affecting Sleep
Understanding the concepts of physical dependence,...
Obesity
Drug Dosing: Obese Patients
REM Sleep Behavior Disorder
RBD is significantly associated with...

