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Updated: Jul 3, 2026
05:22
Rapid Collection of Floral Fragrance Volatiles using a Headspace Volatile Collection Technique for GC-MS Thermal Desorption Sampling
Published on: December 10, 2019
Fragrance material review on sclareol
S P Bhatia1, D McGinty, C S Letizia
1Research Institute for Fragrance Materials Inc., Woodcliff Lake, NJ 07677, USA. sbhatia@rifm.org
Summary
This review examines the safety of sclareol, a fragrance ingredient, focusing on its toxicologic and dermatologic effects. The findings assess its suitability for cosmetic and personal care product applications.
Area of Science:
- Toxicology
- Dermatology
- Cosmetic Science
Background:
- Sclareol is a naturally occurring diterpene alcohol used as a fragrance ingredient.
- Its use in consumer products necessitates a thorough safety assessment.
Purpose of the Study:
- To review the toxicologic and dermatologic data available for sclareol.
- To evaluate the safety of sclareol as a fragrance ingredient.
Main Methods:
- Literature review of toxicologic studies.
- Review of dermatologic assessments and human data.
- Analysis of regulatory information and safety assessments.
Main Results:
- Sclareol exhibits a low order of acute toxicity.
- Dermal irritation and sensitization potential are generally low.
- No significant systemic toxicity concerns identified at typical use concentrations.
Conclusions:
- Sclareol is considered safe for use as a fragrance ingredient at current concentrations.
- Further research may be warranted for specific exposure scenarios.
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