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Updated: Jul 3, 2026

Rapid Collection of Floral Fragrance Volatiles using a Headspace Volatile Collection Technique for GC-MS Thermal Desorption Sampling
Published on: December 10, 2019
Fragrance material review on hydroxycitronellol.
A Lapczynski1, S P Bhatia, C S Letizia
1Research Institute for Fragrance Materials Inc., Woodcliff Lake, NJ 07677, USA. alapczynski@rifm.org
This review examines the safety of hydroxycitronellol, a common fragrance ingredient. It assesses toxicologic and dermatologic data to determine its safe use in consumer products.
Area of Science:
- Toxicology
- Dermatology
- Cosmetic Science
Background:
- Hydroxycitronellol is a widely used fragrance ingredient in various consumer products.
- Understanding its toxicologic and dermatologic profile is crucial for consumer safety.
- Previous safety assessments may require updates based on current data.
Purpose of the Study:
- To conduct a comprehensive toxicologic and dermatologic review of hydroxycitronellol.
- To evaluate the safety of hydroxycitronellol as a fragrance ingredient.
- To provide an updated assessment of potential risks associated with hydroxycitronellol exposure.
Main Methods:
- Literature review of existing toxicologic studies.
- Analysis of dermatologic data, including irritation and sensitization potential.
- Evaluation of exposure data from fragrance use.
Main Results:
- The review synthesizes available data on hydroxycitronellol's safety.
- Potential for skin irritation and sensitization is assessed.
- Overall toxicologic profile is evaluated in the context of typical use concentrations.
Conclusions:
- Hydroxycitronellol is generally considered safe for use as a fragrance ingredient at current concentrations.
- Further research may be warranted for specific exposure scenarios.
- The review supports the continued use of hydroxycitronellol in cosmetic products based on available evidence.
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