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Updated: Jul 3, 2026
05:22
Rapid Collection of Floral Fragrance Volatiles using a Headspace Volatile Collection Technique for GC-MS Thermal Desorption Sampling
Published on: December 10, 2019
Fragrance material review on nerol.
A Lapczynski1, R J Foxenberg, S P Bhatia
1Research Institute for Fragrance Materials Inc., Woodcliff Lake, NJ 07677, USA. alapczynski@rifm.org
Summary
This review examines the toxicologic and dermatologic effects of nerol, a common fragrance ingredient. It provides a comprehensive safety assessment for its use in consumer products.
Area of Science:
- Toxicology
- Dermatology
- Fragrance Chemistry
Background:
- Nerol is a naturally occurring acyclic monoterpene alcohol.
- It is widely utilized as a fragrance ingredient in perfumes, cosmetics, and household products.
- Understanding its toxicologic and dermatologic profile is crucial for consumer safety.
Purpose of the Study:
- To conduct a comprehensive review of the toxicologic data for nerol.
- To evaluate the dermatologic effects associated with nerol exposure.
- To assess the safety of nerol as a fragrance ingredient.
Main Methods:
- Literature search of toxicologic databases (e.g., PubMed, TOXNET).
- Review of dermatologic studies and case reports.
- Analysis of regulatory assessments and industry-sponsored research.
Main Results:
- Nerol exhibits low acute oral and dermal toxicity.
- Skin sensitization potential is generally considered low but can occur in susceptible individuals.
- No significant evidence of mutagenicity or carcinogenicity was found.
Conclusions:
- Nerol is considered safe for use as a fragrance ingredient at typical concentrations.
- Potential for skin sensitization warrants consideration in product formulation.
- Further research may be beneficial for specific exposure scenarios.
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