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Published on: December 10, 2019
Fragrance material review on tetrahydrolinalool
A Lapczynski1, R J Foxenberg, S P Bhatia
1Research Institute for Fragrance Materials Inc., Woodcliff Lake, NJ 07677, USA. alapczynski@rifm.org
Summary
This review examines the safety of tetrahydrolinalool, a common fragrance ingredient. It assesses potential toxicologic and dermatologic effects for consumer safety.
Area of Science:
- Toxicology
- Dermatology
- Fragrance Chemistry
Background:
- Tetrahydrolinalool is widely utilized as a fragrance ingredient in various consumer products.
- Understanding its toxicologic and dermatologic profile is crucial for assessing consumer safety.
- Previous safety data may be limited or require consolidation.
Purpose of the Study:
- To conduct a comprehensive toxicologic and dermatologic review of tetrahydrolinalool.
- To evaluate the safety of tetrahydrolinalool as a fragrance ingredient.
- To identify any potential risks associated with its use.
Main Methods:
- Literature review of existing toxicologic studies.
- Analysis of dermatologic data, including irritation and sensitization potential.
- Assessment of exposure scenarios in consumer products.
Main Results:
- Summarizes available data on tetrahydrolinalool's systemic toxicity.
- Details findings regarding skin irritation and sensitization.
- Evaluates the relevance of animal study data to human health.
Conclusions:
- Tetrahydrolinalool is generally considered safe for use as a fragrance ingredient at typical concentrations.
- No significant toxicologic or dermatologic concerns were identified based on current data.
- Further research may be warranted for specific exposure scenarios or sensitive populations.
