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Published on: April 2, 2021
[Retinopathy of prematurity complicated by late glaucoma: a case report]
1Service d'ophtalmologie, Fondation Ophtalmologique Rothschild, Paris, France. celinefaureb@yahoo.fr
Insights
Late-onset glaucoma can occur decades after retinopathy of prematurity (ROP) treatment. Prompt diagnosis requires awareness of ROP history, as iris vessel changes can mimic neovascular glaucoma.
Area of Science:
- Ophthalmology
- Retinal Diseases
- Glaucoma
Background:
- Retinopathy of prematurity (ROP) is a significant cause of visual impairment in premature infants.
- Late-onset complications of ROP, such as glaucoma, can manifest decades after initial treatment.
- Understanding the long-term sequelae of ROP is crucial for effective patient management.
Observation:
- A 54-year-old woman with a history of prematurity presented with acute intraocular pressure elevation in her right eye.
- Clinical examination revealed prominent iris vessel dilatation and corneal edema, obscuring fundus view.
- Ocular echography was normal, but the fellow eye showed signs of cicatricial-stage retinopathy of prematurity.
Findings:
- The patient was diagnosed with neovascular glaucoma, likely a late complication of retinopathy of prematurity.
- Treatment involved cyclodestruction and transscleral cryoapplication to control intraocular pressure.
- Fundus examination post-resolution of corneal edema showed peripheral retinal photocoagulation scars and iridocorneal synechiae.
Implications:
- Prominent iris vessel dilatation in ROP patients can be mistaken for rubeosis, potentially leading to misdiagnosis.
- A thorough patient history, including prematurity, is essential for accurate diagnosis of late ROP complications.
- This case highlights the importance of long-term ophthalmic monitoring for individuals treated for retinopathy of prematurity.
Introduction:
We report the case of an acute rise in intraocular pressure occurring decades after the treatment for prematurity (ROP).
Case Report:
A 54-year-old preterm woman presented an acute rise in intraocular pressure in her right amblyopic eye. Prominent dilatation of iridal vessels was noted. Fundus was not visible at that time because of corneal edema. Ocular echography was normal. The fellow eye showed temporal attraction of temporal vessels suggestive of retinopathy of prematurity at the cicatricial stage. Neovascular glaucoma was postulated and pressure control was obtained after cyclodestruction and transscleral cryoapplication. After resolution of corneal edema, fundus examination revealed extensive peripheral retinal photocoagulation scars. Iridocorneal angle presented extensive iridocorneal synechias without true new vessels. Visual acuity remained limited to hand motion.
Conclusion:
Prominent iris dilatation seen in some preterm patients can mimic rubeosis, and, in the present case, mislead to a diagnosis of neovascular glaucoma. Diagnosis can be difficult if the patient is not specifically asked for a history of prematurity. The case underlines the notion that ROP patients may present very late complications of the disease.
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