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Updated: Jul 3, 2026

Technique for Studying Arthropod and Microbial Communities within Tree Tissues
Published on: November 16, 2014
Cutting the forest to see a single tree?
1Harvard Medical School, Department of Biological Chemistry and Molecular Pharmacology, 240 Longwood Avenue, SGM204A, Boston, Massachusetts 02115, USA. antoine_van_oijen@hms.harvard.edu
Abstract:
The development of single-molecule tools has significantly impacted the way we think about biochemical processes. Watching a single protein in action allows us to observe kinetic details and rare subpopulations that are hidden in ensemble-averaging techniques. I will discuss here the pros and cons of the single-molecule approach in studying ligand binding in macromolecular systems and how these techniques can be applied to characterize the behavior of large multicomponent biochemical systems.
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